Protein Labeling Reagents
Biotium Insulin(E2-E3), CF568 conjugate, 0.1mg/mL
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
Biotium CD10(FR4D11), CF568 conjugate, 0.1mg/mL
CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA)) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
STEMCELL Technologies LysoBrite™ Lysosome Dye, Green, Size: 500 Tests
LysoBrite™ dyes are fluorescent dyes that selectively stain lysosomes and other acidic organelles. Due to their hydrophobic nature, LysoBrite™ dyes permeate live cells and selectively accumulate in the lysosomes via the lysosome’s pH gradient. The fluorescence property of these dyes significantly increases within the lysosome’s acidic environment; this fluorescence can be measured using flow cytometry and fluorescence imaging. Due to their selective fluorescence inside lysosomes, LysoBrite™ dyes provide low background and high contrast during imaging. They can be used with proliferating and non-proliferating cells, and are suitable for suspension and adherent cells.
Biotium ViaFluor 647, 50 uL
ViaFluor Live Cell Microtubule Stains are cell-permeable taxol probes for imaging the microtubule cytoskeleton in live cells. Available with blue, green, or far-red fluorescence.
Revvity Health Sciences Inc IVISense 800 NHS Fluorescent Dye (5 mg) (VivoTag)
IVISense 800 NHS Fluorescent Dye (5 mg) (VivoTag)
![eMolecules Broadpharm / BDP 581/591 tetrazine / 1mg / 761705821 / BP-28949 / / / [null] / 575.430 / C32H28BF2N7O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502460525.PNG-250.jpg)
eMolecules Broadpharm / BDP 581/591 tetrazine / 1mg / 761705821 / BP-28949 / / / [null] / 575.430 / C32H28BF2N7O
Broadpharm / BDP 581/591 tetrazine / 1mg / 761705821 / BP-28949 / / / [null] / 575.430 / C32H28BF2N7O
Santa Cruz Biotechnology Chromeo™ P503 | 1mg
Chromeo™ P503 detects proteins and peptides by exhibiting a color change from blue to red. After binding to primary amines, it undergos a large shortwave spectral shift of more than 100nm that is visible to the naked eye. There is also a large increase in quantum yield that changes the non- or only weakly fluorescent dye into a bright fluorescent conjugate. The shift of the absorption & emission bands together with the increased fluorescence quantum yield effectively eliminates background from any unbound dye. In addition, because unbound the pyrylium dye is hydrolyzed during the labeling procedure, there is no need for purification following the simple one-step, room-temperature incubation. The labeled protein is ready to use immediately, and any possible background from the unbound dye is eliminated. Due to the unique conjugation mechanism, proteins labeled with Py-Dyes maintain their native charge and isoelectric point.